Glomerular disease is a condition that affects the glomeruli, the units of the kidney that filter waste and remove extra fluids from the blood. It is the third leading cause of kidney failure in the U.S. and commonly recurs following kidney transplant surgery, shortening the life of the new kidney.

It remains unclear why glomerular disease recurs in some patients, while not in others. Many physicians tried to elucidate this challenging problem within kidney transplant research. Most of these studies were only based on few patients, making it difficult to establish evidence-based clinical guidelines.

We believe collaboration is the only way forward to effectively tackle this rare and challenging disease entity. This is why our team founded the TANGO Consortium, an international network of patients, physicians, researchers, and industry partners that collaborate to study glomerular disease recurrence after kidney transplantation.

For Patients

Glomerular disease is the third leading cause of kidney failure in the U.S. and commonly recurs following kidney transplant surgery, shortening the life of the new kidney. There are many important questions to be answered for patients with glomerular disease recurrence.

• Why do certain treatments work for some patients with glomerular disease recurrence after transplant, but not for others?
• Are there any gene mutations that make patients more susceptible to glomerular disease recurrence after transplant?
• Are there any novel biomarkers in the blood that can be used to detect disease activity and monitor treatment response?

• Why do certain treatments work for some patients with glomerular disease recurrence after transplant, but not for others?
• Are there any gene mutations that make patients more susceptible to glomerular disease recurrence after transplant?
• Are there any novel biomarkers in the blood that can be used to detect disease activity and monitor treatment response?

By participating in our study, you allow us to find these answers, that could help you and your physician make better decisions about your health. 

Any patient diagnosed with glomerular disease, currently on the kidney transplant waitlist and based in the United States can join our study by voluntarily donating samples and health information. 

To learn more about our ongoing patient trial, please complete the screening survey below.